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Connections abstract

The IND is the regional resource for advancing neuroscience research. We are uniquely positioned to make discoveries to improve the lives of patients who may suffer from neurological diseases and injury.

The IND is all about team-based scientific discovery. Recent initiatives by our translational research teams have led to successful applications to the NIH for the KU Alzheimer's Disease Research Center and NeuroNEXT, which is a joint effort between KU Medical Center and Children's Mercy Hospital supporting clinical trials for neurological therapies.

The IND has advanced major research programs by recruiting members in complementary disciplines and using established scientific cores to develop clinical models that can be used to explore therapies. One example is the IND's Spinal Cord Injury Repair Program. This translational research enterprise is supported primary through a $4 million philanthropic partnership, and is focused on brain-computer interfaces and patient-derived genetically engineered stem cells as potential therapeutic strategies. This initiative involves more than 18 faculty investigators from several institutions and draws heavily on IND-affiliated core services in behavioral analysis, genetic engineering, and imaging.

A joint program between KUMC and Children's Mercy Hospital Pediatrics Genomics division, funded by the Kansas City Area Life Sciences Institute, is another example. In this program, our genetic engineering and transgenic mouse facilities use gene sequencing data from afflicted patients to generate mouse models, which are then characterized by our behavioral testing and our imaging cores, and potential therapies are investigated by our disease model and testing facility.

The IND is poised to create similar teams of experts and muster an array of cutting-edge core scientific technologies to conduct similar investigations in any of the other 20 neurological disorders that lie within the focus of the IND.

Last modified: Aug 27, 2018
IND by the Numbers